Science and technology have an important role in maintaining the ecosystem of the universe. In science, the philosophy of science paradigm was put forward to integrate metaphysics with the physical, micro, and macro elements and the general with the. This study aims to explore the knowledge whose essence comes from thoughts about human philosophy, namely the basis of ontology, epistemology, and axiology. The deductive descriptive method was used to explain in general the view of science in the awareness of human moral formation from a dialectical process. The root of the multidimensional paradigm in examining a scientific truth in the dialectical process is by integrating the ontology, epistemology, and axiology aspects based on epistemic, scientific, and cultural values of society.